Difference between Ail and AleA trivial definition for ail: it means we are ailing. Ail means to feel sick, be ill or have pain. In other words, to suffer from an ailment: This medicine is good for whatever may ail you.
Ale, on other hand, is an altogether different ball game. It refers to a bitter beer (we all know what beer is, don’t we)
Usage example that uses these 2 words: If you drink too much ale, you will ail for sure.